Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the COVID-19 pandemic.After the success of therapeutics and worldwide vaccination, the long-term sequelae of SARS-CoV-2 infections are yet to be determined.Common symptoms of COVID-19 include the loss of taste and smell, suggesting SARS-CoV-2 infection has a potentially detrimental
Development of a standardized in vitro model to reproduce hydrophilic acrylic intraocular lens calcification
Abstract Opacification through calcification of hydrophilic acrylic intraocular lenses (IOL) is a severe complication after cataract surgery.Causing symptoms that range from glare through to severe vision loss, the only effective therapy is explantation of the opacified IOL so far.Although IOL calcification is a well-described phenomenon, its patho
X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues.Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.Here, we investigated the Right Link Arm role of HUWE1 in the female reproductive system.Homozygous deletion of
Seeds of Myth: Exotic Disease Theory and Deconstructing the Australian Narrative of Indigenous Depopulation
Abstract The theory that the rapid depopulation of Indigenous people post-colonisation was largely caused by European introduced or exotic disease to which Indigenous people had no immunity resonates through most narratives of the early years of colonisation.The question of whether this narrative is based on sound medical evidence or is better plac