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SARS-CoV-2 infection in microglia and its sequelae: What do we know so far?

SARS-CoV-2 infection in microglia and its sequelae: What do we know so far?

July 14, 2025 Category: Blog

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the COVID-19 pandemic.After the success of therapeutics and worldwide vaccination, the long-term sequelae of SARS-CoV-2 infections are yet to be determined.Common symptoms of COVID-19 include the loss of taste and smell, suggesting SARS-CoV-2 infection has a potentially detrimental

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Development of a standardized in vitro model to reproduce hydrophilic acrylic intraocular lens calcification

July 14, 2025 Category: Blog

Abstract Opacification through calcification of hydrophilic acrylic intraocular lenses (IOL) is a severe complication after cataract surgery.Causing symptoms that range from glare through to severe vision loss, the only effective therapy is explantation of the opacified IOL so far.Although IOL calcification is a well-described phenomenon, its patho

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X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development

July 14, 2025 Category: Blog

Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues.Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.Here, we investigated the Right Link Arm role of HUWE1 in the female reproductive system.Homozygous deletion of

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Seeds of Myth: Exotic Disease Theory and Deconstructing the Australian Narrative of Indigenous Depopulation

July 14, 2025 Category: Blog

Abstract The theory that the rapid depopulation of Indigenous people post-colonisation was largely caused by European introduced or exotic disease to which Indigenous people had no immunity resonates through most narratives of the early years of colonisation.The question of whether this narrative is based on sound medical evidence or is better plac

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